Blue screen when playing PC games. What do I do?

Whenever I play Diablo 2 Lord of Destruction or World of Warcraft, which, thankfully, I no longer play, I will get a blue screen. I use an Acer computer, model ASE 380-UD421A, my video card is an NVIDIA Ge Force 6100 nForce 430, and I'm not sure what my sound card is. All my drivers are current, and this issue doesn't happen when I play Warcraft III or Starcraft. I'm running Vista, I don't know if that has anything to do with it. I'm hoping this is fixable without doing anything major. All help is appreciated.